FoodFacts.com found very exciting news regarding the role of nutrition in the fight against Alzheimer’s disease. Alzheimer’s is a concern for a large portion of the population and robs family’s of their loved ones every day. We’re pleased to see the research being done to combat the disease highlight nutrition as a possible bright light in an otherwise fairly dark landscape.
A small pilot study coming out of the David Geffen School of Medicine at UCLA has identified how Vitamin D3 and Omega-3 Fatty Acids may aid the body’s immune system, enhancing its ability to clear amyloid plaques from the brain. Amyloid plaques are a major feature of Alzheimer’s disease.
The study identified the genes regulated by Vitamin D3 and the Omega-3 Fatty Acid, DHA that might control inflammation and boost plaque clearance. Previous laboratory work by the team helped shed light on how Vitamin D3 can clear amyloid-beta. That’s the abnormal protein in the plaque that builds up in the brains of those afflicted with Alzheimer’s Disease. This new study builds on that research and goes on to highlight the role of Omega-3 DHA.
The researchers took blood samples from a population of Alzheimer’s patients and a population of healthy patients. They isolated macrophages (important immune cells) from the blood. These are the immune cells that absorb amyloid-beta and other waste products in the brain and the rest of the body. Those immune cells were incubated overnight with amyloid-beta — and in addition, some of them were also incubated with an active form of Vitamin D3 and some of them with an active form of Omega-3 Fatty Acid DHA.
The immune cells from Alzheimer’s patients that were incubated with Vitamin D3 and the Omega-3 Fatty Acid DHA had an increased ability ability to absorb the amyloid-beta. They also inhibited the death of the immune cells that is induced by amyloid-beta.
While pleased with the results, researchers pointed out that more study is needed. They seek to clarify the balance of supplementation with Vitamin D3 and Omega-3 Fatty Acids to maximize the clearing of amyloid-beta. They are looking to conduct a larger study to confirm these initial findings.
FoodFacts.com is encouraged by these findings as science seeks to find an answer for this serious and heartbreaking condition affecting older and younger populations worldwide. Nutrition can hold keys to solutions for a variety of different conditions and we are hopeful that this new research points to new hope for Alzheimer’s Disease.
Read more here: http://www.sciencedaily.com/releases/2013/02/130205131629.htm